Tag Archives: quote

Need to make a molecule? Ask this AI for instructions

Need to make a molecule? Ask this AI for instructions
http://www.nature.com/articles/d41586-018-03977-w #DeepLearning to do better #retrosynthesis. Perhaps other things in chemistry could be learned as well!

QT:{{”
“The tool, described in Nature on 28 March1, is not the first software to wield artificial intelligence (AI) instead of human skill and intuition. Yet chemists hail the development as a milestone, saying that it could speed up the process of drug discovery and make organic chemistry more efficient.

“What we have seen here is that this kind of artificial intelligence can capture this expert knowledge,” says Pablo Carbonell, who designs synthesis-predicting tools at the University of Manchester, UK, and was not involved in the work. He describes the effort as “a landmark paper”.”
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10 Places With Spectacular Views Of This Summer’s Total Solar Eclipse

How far are you from…spots to watch the #Eclipse?
https://www.buzzfeed.com/zahrahirji/spectacular-views-of-the-eclipse Does anyone know what we’ll see in CT on 8/21? A partial one?

QT:{{”
“The zone of totality is about 70 miles wide and stretches diagonally across the middle of the country from Oregon to South Carolina. Hundreds of towns and cities in 12 states fall fully within the zone. And the closer you are to the zone’s center, the longer the full eclipse will last. While the maximum possible duration of the full eclipse is about 2 minutes and 40 seconds, the partial eclipse will last upward of two hours in most places nationwide.”
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NAR Breakthrough Article: denovo-db: a compendium of human de novo variants

.@denovodb: a compendium of [initially ~33K] human de novo variants w. phenotype, freely downloadable as a TSV table
https://academic.OUP.com/nar/article-lookup/doi/10.1093/nar/gkw865

QT:{{”
As of July 2016, denovo-db contained 40 different studies and 32,991 de novo variants from 23,098 trios. Database features include basic variant information (chromosome location, change, type); detailed annotation at the transcript and protein levels; severity scores; frequency; validation status; and, most importantly, the phenotype of the individual with the variant.
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denovo-db.gs.washington.edu/denovo-db/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5210614/